Journal of Emergency Health Care
Formerly known as: International Journal of Medical Investigation
Volume 12, Issue 3 (10-2023)
J Emerg Health Care 2023, 12(3): 126-132 |
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Shabestari M S, Moghadam Y J, Azimpour S, Ghaedi M, Sohrabpour M. Comparison Of Pathologic Differences In Adenoid Tissues Of Allergic Patients With Non-Allergic Patients. J Emerg Health Care 2023; 12 (3) :126-132
URL: http://intjmi.com/article-1-1063-en.html
URL: http://intjmi.com/article-1-1063-en.html
Mahnaz Sadeghi Shabestari 
, Yalda Jabbari Moghadam , Saeedeh Azimpour , Mojtaba Ghaedi , Mojtaba Sohrabpour *
, Yalda Jabbari Moghadam , Saeedeh Azimpour , Mojtaba Ghaedi , Mojtaba Sohrabpour *
Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.
Abstract: (633 Views)
Background: Tonsils are masses of lymphatic tissue that play a significant role in protecting the body against pathogens and allergens due to their location in the upper respiratory and gastrointestinal tracts.
Method: Fifty patients with allergic adenotonsillar hypertrophy and fifty patients with non-allergic adenotonsillar hypertrophy were selected as candidates for surgery by specialist. Obtained samples were sent to the pathology department and then compared in terms of pathology, number of eosinophil, lymphocytes, neutrophils and the presence or absence of lipids by a specialist.
Results: That among all the studied variables, family history of asthma and allergic rhinitis, history of asthma and allergic rhinitis in the patient, positive result of prick test (air allergen, food and mite) and lymphocyte count were significantly higher in patients with allergic adenotonsillar hypertrophy than in patients with non-allergic adenotonsillar hypertrophy. Neutrophil count was significantly higher in patients with non-allergic adenotonsillar hypertrophy than in patients with allergic adenotonsillar hypertrophy (P-value <0.001). In other variables such as eosinophil count, presence of lipids, gender, age, family history of tonsillitis, smoking in the family, largeness of pharyngeal tonsils, diagnosis method, apnea, persistent night snoring and continuous mouth breathing, there was no statistically significant difference between the two groups (P-value> 0.05).
Conclusion: The significant difference between clinical and pathologic characteristics of adenoid tissues of allergic patients and non-allergic patients suggest that special attention should be paid for diagnosis and treatment of these patients. However, more comprehensive study with a larger sample size is needed to evaluate this issue more accurately.
Method: Fifty patients with allergic adenotonsillar hypertrophy and fifty patients with non-allergic adenotonsillar hypertrophy were selected as candidates for surgery by specialist. Obtained samples were sent to the pathology department and then compared in terms of pathology, number of eosinophil, lymphocytes, neutrophils and the presence or absence of lipids by a specialist.
Results: That among all the studied variables, family history of asthma and allergic rhinitis, history of asthma and allergic rhinitis in the patient, positive result of prick test (air allergen, food and mite) and lymphocyte count were significantly higher in patients with allergic adenotonsillar hypertrophy than in patients with non-allergic adenotonsillar hypertrophy. Neutrophil count was significantly higher in patients with non-allergic adenotonsillar hypertrophy than in patients with allergic adenotonsillar hypertrophy (P-value <0.001). In other variables such as eosinophil count, presence of lipids, gender, age, family history of tonsillitis, smoking in the family, largeness of pharyngeal tonsils, diagnosis method, apnea, persistent night snoring and continuous mouth breathing, there was no statistically significant difference between the two groups (P-value> 0.05).
Conclusion: The significant difference between clinical and pathologic characteristics of adenoid tissues of allergic patients and non-allergic patients suggest that special attention should be paid for diagnosis and treatment of these patients. However, more comprehensive study with a larger sample size is needed to evaluate this issue more accurately.
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