Journal of Emergency Health Care

fa Mechanical Ventilation and Anesthesia Strategies in Patients with Acute Respiratory Failure Due to Guillain-Barré Syndrome عمومى General پژوهشي Research Background: This narrative review delves into the nuances of mechanical ventilation and tracheostomy in the context of Guillain-Barré Syndrome (GBS), aiming to provide a comprehensive understanding of the indications, anesthesia management, ventilation settings, and related considerations. Method: The review was conducted by analyzing relevant literature and studies that address the use of mechanical ventilation and aanesthesiaa in GBS patients Results: Indications to initiate mechanical ventilation encompass acute respiratory distress/arrest, hypoxia, hypercarbia, and acidosis, failure of non-invasive ventilation. Early Mechanical Ventilation (EMV) might be considered in cases of impaired swallowing. Anesthesia management poses challenges due to altered responses to neuromuscular blocking drugs (NMBDs); while sucssefull general anesthesia cases are reported in literature. While depolarizing agents like succinylcholine are contraindicated, non-depolarizing agents such as rocuronium and vecuronium may be used with caution. The role of sugammadex in reversing NMBDs' effects is explored but not yet fully established. Tracheostomy might be considered for patients requiring prolonged mechanical ventilation. Conclusion: This narrative review provides information about the multifaceted considerations of mechanical ventilation and anesthesia in GBS.   Guillain-Barré Syndrome, Mechanical Ventilation, Anesthesia, Pain Management. 178 184 http://intjmi.com/browse.php?a_code=A-10-1-536&slc_lang=fa&sid=1 Mansoor Deilami 10031947532846005848 10031947532846005848 No Department of Anesthesiology and Critical Care, 5 Azar Hospital, Golestan University of Medical Sciences, Golestan, Iran Reza Sahraei 10031947532846005849 10031947532846005849 No Associate Professor, Department of Anesthesiology, Critical Care and Pain Management Research Center, Jahrom University of Medical Sciences, Jahrom, Iran Mohammad Sadegh Sanie Jahromi 10031947532846005850 10031947532846005850 No Associate Professor, Department of Anesthesiology, Critical Care and Pain Management Research Center, Jahrom University of Medical Sciences, Jahrom, Iran Majid Vatankhah 10031947532846005851 10031947532846005851 No Associate Professor, Department of Anesthesiology, Anesthesiology , Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran Mehrdad Malekshoar 10031947532846005852 10031947532846005852 No Associate Professor, Department of Anesthesiology, Anesthesiology ,Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran. Pourya Adibi 10031947532846005853 10031947532846005853 No Assistant Professor, Department of Anesthesiology, Anesthesiology, Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran. , Elahe Rahmanian 10031947532846005854 10031947532846005854 No Department of Anesthesiology, Critical Care and Pain Management Research Center, Jahrom University of Medical Sciences, Jahrom, Iran Hasan Zabetian 10031947532846005855 10031947532846005855 No Associate Professor, Department of Anesthesiology, Critical Care and Pain Management Research Center, Jahrom University of Medical Sciences, Jahrom, Iran Tayyebeh Zarei 10031947532846005856 10031947532846005856 Yes Assistant Professor, Department of Anesthesiology, Anesthesiology, Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.